0
Other Articles |

ATHEROSCLEROSIS

David Monk Adams
JAMA. 1950;143(2):198. doi:10.1001/jama.1950.02910370048023.
Text Size: A A A
Published online

ABSTRACT

To the Editor:—  In a Current Comment, in The Journal, January 28, page 262, mention is made of experiments in which dietary hypercholesteremia in the rabbit resulted consistently in the production of atherosclerosis. However, in the alloxan diabetic rabbit this effect was not produced. This work was difficult to reconcile with the higher incidence of atherosclerosis which occurs in human diabetes, until the publication of J. B. Firstbrook (Science111:31 [Jan. 13] 1950), which was not included in your comment, possibly because it had not yet appeared when your article was being prepared. In normal rabbits he has demonstrated the importance of differences in the change of weight during the experiment on the production of atherosclerosis. If the food intake of rabbits fed cholesterol was diminished, the incidence of atherosclerosis was also diminished. Dr. Firstbrook's work makes it appear that the low incidence of experimental atherosclerosis in rabbits rendered

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();