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USE OF DIETHYLSTILBESTROL IN ORCHITIS DUE TO MUMPS

ROBERT J. NORTON, M.D.
JAMA. 1950;143(2):172-174. doi:10.1001/jama.1950.02910370022007.
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Beyond the age of puberty involvement of the sexual glands as a complication of epidemic parotitis, particularly in the male, occurs in 18 to 35 per cent of cases. About 80 per cent of these involvements appear during the first eight days of mumps. A few cccur a considerable time after the epidemic parotitis has subsided. Little difference in the incidence of epididymo-orchitis is noted whether the patient is confined to bed or permitted to walk about during convalescence.1 The onset is usually characterized by recurrence of fever, decided pain in and swelling of one or both testicles.

In 1912 G. G. Smith2 and in 1942 Wesselhoeft and Vose3 recommended incision of the tunica albuginea testis to prevent pressure atrophy of the testicles and consequent loss of spermatogenic function. In the past few years several authors have tried a more conservative approach for prophylaxis and treatment of

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