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ARTICLE |

MEDICATED TISSUE

I. Phillips Frohman, M.D.
JAMA. 1954;154(5):438. doi:10.1001/jama.1954.02940390062024.
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ABSTRACT

To the Editor:—  In recent weeks one manufacturer of paper nasal tissues has placed on the market tissues impregnated with alkyl dimethylbenzylammonium chloride (C8H17C18H37). Approximately six weeks ago, I was called to the home of a 47-year-old white woman whose chief complaints were hoarseness, a feeling of fulness in the nose and frontal sinuses, sore throat, and nasal discharge. Her clinical symptoms resembled an upper respiratory type of infection. Her temperature was 98.6 F, and her eyes showed no redness or tearing. There was much nasal congestion with redness and nasal discharge. The dorsum of the tongue and the nasopharynx were slightly edematous and quite red. The chest was normal, with blood pressure 125/80 mm. Hg, pulse 88, and respirations 18. This patient was disturbed by a hacking cough. The striking comment made by the patient was the statement that she had a

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