JAMA. 1932;99(22):1864. doi:10.1001/jama.1932.02740740048015.
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Although rickets has long been recognized as an important disorder, it failed to receive the serious attention that it unquestionably deserves prior to the advent of modern studies of vitamins. The elucidation of some of the characteristic features of rickets came from the experimental laboratory. The relations of the supply of calcium and phosphorus, as well as vitamin D, or some physiologic equivalent of the latter, to the genesis and cure of the malady have become clearly established. Clinical application of this knowledge followed promptly, so that antirachitic measures are understood and recommended widely as a part of the modern child welfare program. The situation is somewhat analogous to that which applies to the management and prophylaxis of scurvy. Thanks to an understanding of the origin, prevention and treatment of the latter disease it has rapidly become eliminated as a serious menace to health and as a prominent factor in


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