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RABIES IN BIRMINGHAM, ALABAMA:  HUMAN MORTALITY AS AFFECTED BY ANTIRABIES TREATMENTS

GEORGE A. DENISON, M.D.; J. D. DOWLING, M.D.
JAMA. 1939;113(5):390-395. doi:10.1001/jama.1939.02800300020006.
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In this paper we deal with the experiences of a local health department in the prevention of rabies among human beings. We are especially concerned with those problems which confront the physician; namely, the value of antirabies vaccine and indication for its administration.

The difficulties involved in maintaining continuous programs for the enforced confinement of dogs, along with the failure to find other effective control measures, has greatly intensified the problem of rabies. Through failure to control the dog, increased reliance has been placed in secondary control measures. Antirabies vaccine has been administered to an ever increasing number of persons who become exposed to an ever increasing number of rabid dogs.

The original Pasteur treatment and its several modifications have become generally accepted as reasonably safe and highly effective in preventing rabies among human beings. This, together with the ready availability of the vaccine, the ease of its administration, the

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