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Leon N. Sussman, M.D.; Ira B. Cohen, M.D.
JAMA. 1954;154(1):82. doi:10.1001/jama.1954.02940350084029.
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To the Editor:—  There is a difference of opinion over the merits of filtering blood immediately before transfusion or administering blood to the patient through an intravenous set with a filter "in the line." In the prefiltering method, the blood is filtered by means of a closed system through a regulation filter and short length of tubing. The tubing leads into an inverted vacuum bottle. The bottle is inverted to prevent any marked agitation. The last few drops of blood from the filter are used for "rapid cell typing." The blood can then be administered through the usual intravenous set without additional filtering at the bedside. The alternate method requires that the blood be administered to the recipient with a special intravenous set having a filter in the line.The advantages of prefiltering the blood are: 1. "Filter trouble," occasioned by clots or fibrin blocking the filter and preventing the


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