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PELLAGRA OF KENTUCKY MOUNTAIN FOLK:  AMBULATORY TREATMENT WITH NICOTINIC ACID

JOHN H. KOOSER, M.D.; M. A. BLANKENHORN, M.D.
JAMA. 1939;112(25):2581-2584. doi:10.1001/jama.1939.02800250005002.
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Since remarkable results of nicotinic acid treament of acute pellagra have been reported from numerous sources1 it naturally follows that the same treatment should be tried in recurrent and chronic forms of the disease as seen in an ambulatory clinic. The application of dietary measures, even with the aid of yeast, has not been satisfactory with the ambulatory patient. Now, with an inexpensive and easily administered remedy, so-called control of the disease could be attempted. At the invitation of the Frontier Nursing Service, Inc., of Kentucky and the Health Department of Perry County, the treatment of ambulatory cases among mountain folk was started in April 1938 in a public health clinic. The study and methods of treatment were similar to those used by the University of Cincinnati, under the guidance of Dr. Tom D. Spies, at Birmingham, Ala.2 Unlike the clinic treatment recently described from Augusta, Ga.,3

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