This thesis by the son of the renowned Argentinean physiologist is a comprehensive review of our knowledge concerning the diabetogenic action of the anterior pituitary lobe. The book is divided into three sections. The first deals with the history of our concepts of the role of the hypophysis in carbohydrate metabolism. The second is a detailed analysis of the metabolic actions of the anterior pituitary of the toad. This animal has been used extensively by the Houssay school for endocrine investigations. The last section deals with mammalian pituitary physiology in its metabolic aspects. The bibliography is excellent and well arranged. The index is poor. In view of the unsettled conditions in Argentina in the past several years, it is interesting to note that the author remarks in his preface that 'the development of science is defective or impossible without liberty, and culture rapidly decays when liberty is restricted.'