We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |


JAMA. 1946;132(5):272-278. doi:10.1001/jama.1946.02870400020004.
Text Size: A A A
Published online


Penicillin spray, as used in this report, is produced by a hand-operated bulb atomizer and is utilized by inhalation. The patient holds his breath at the end of the inspiration, allowing the suspended penicillin to settle on the infected mucous membranes. The terms aerosol penicillin and penicillin spray are used synonymously. An aerosol is a fine suspension of a liquid or solid in a gaseous medium.

Penicillin is perhaps the greatest life-saving drug today. The greatest drawback to its general use by the country practitioner especially, and to a lesser degree by his urban brother, in this day of overcrowded hospitals and scarcity of nurses is that its use by the accepted intramuscular or intravenous routes requires either hospitalization or the employment of two trained nurses. The use of a hand atomizer to produce a spray of penicillin, which is inhaled to medicate infections of the respiratory tract, removes the


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.