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JAMA. 1946;132(2):82-83. doi:10.1001/jama.1946.02870370028012.
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TWENTY-FIFTH ANNIVERSARY OF THE DISCOVERY OF INSULIN  Twenty-five years ago Banting and Best, working at the University of Toronto, isolated the substance of the pancreas that had the faculty of lowering the blood sugar and enabling a depancreatized dog to survive for an indefinite period. They made their first report before the University of Toronto Physiological Journal Club November 14,1921 at 4 o'clock in room 17. The speakers were Dr. Banting and Mr. Best, and the subject was "Pancreatic Diabetes." The first two papers1 reporting the results of their work were published in February and May 1922. A commemorative meeting to celebrate the twenty-fifth anniversary of the discovery of insulin is being held under the joint auspices of the University of Toronto and the American Diabetes Association from the 16th to the 18th of this month. Many physicians can recall the pathetic state of children with diabetes in

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