Organic microanalysis is an important tool in medical research and other biologic studies. As such this fourth English edition, based on the methods established by Pregl, should be welcomed by microchemical analysts. The book has been revised and edited with much more regard to developments by other than the German workers. A more orderly sequence in the presentation of apparatus, reagents, procedures, calculations, references and notes is a noteworthy improvement over the earlier editions. Although some new subjects are considered, other desirable methods recently developed are not mentioned. As an example, no reference is made of the ninhydrin method for the determination of α-amino nitrogen.