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Council on Pharmacy and Chemistry

JAMA. 1939;112(19):1949-1951. doi:10.1001/jama.1939.02800190063015.
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Hamilton, J. B.:  Treatment of Sexual Underdevelopment with Synthetic Male Hormone Substance , Endocrinology 21:649 ( (Sept.) ) 1937;.
Vest, S. A., Jr., and Howard, J. E.:  Clinical Experiments with the Use of Male Sex Hormone: Use of Testosterone Propionate in Hypogonadism , J. Urol. 40: 154 ( (July) ) 1938;.
Kenyon, A. T.:  The Effect of Testosterone Propionate on the Genitalia, Prostate, Secondary Sex Characters and Body Weight in Eunuchoidism , Endocrinology 23:121 ( (Aug.) ) 1938;.
A well known news weekly has recently given wide publicity to the method adopted by Foss in England of administering to patients testosterone propionate by inunction. Following this work, several firms have put on the market ointments containing testosterone propionate. Foss and also Parkes administered to several eunuchs doses of from 20 to 50 mg. of testosterone propionate in about 2 cc. of ointment daily in order to obtain satisfactory results. The products marketed in this country contain only 2 mg. of the androgen per cubic centimeter of ointment. It is apparent, therefore, that to administer the appropriate amount of active material the patient must anoint himself with from 10 to 25 cc. of ointment daily. This would, of course, make quite a mess.
Miller, N. E., and others:  Mental and Behavioral Changes Following Male Hormone Treatment of Adult Castration, Hypogonadism and Psychic Impotence , Proc. Soc. Exper. Biol. & Med. 38: 538 ( (May) ) 1938;.
Laroche. G., and Bompard, E.:  Essais de traitement de l'impuissance sexuelle masculine par l'hormone male , Progrès méd. 66: 530 ( (April 9) ) 1938;.
Day, R. V., and others:  Sex Hormone Therapy for Prostatism , Am. J. Surg. 39: 100 ( (Jan.) ) 1938;.
Laroche, G., and others:  Prostatic Hypertrophy: Results of Therapy with Testosterone Acetate and Propionate , Presse méd. 45:932 ( (June 23) ) 1937;.
Moore, R. A., and McLellan, A. M.:  A Histological Study of the Effect of the Sex Hormones on the Human Prostate , J. Urol. 40:641 ( (Nov.) ) 1938;.
Clarke, Ruscoe:  Prostate and Endocrine—Control Series , Brit. J. Urol. 9: 254 ( (Sept.) ) 1937;.
Riches, E. W.:  The Use of Male Sex Hormones , Practitioner 140: 60 ( (Jan.) ) 1938;.
Hamilton, J. B.:  Effect of Male Hormones upon the Descent of the Testes , Anat. Rec. 70:533 ( (April 25) ) 1938;.
Kunstadter, R. H.:  Induction of Premature Puberty with Androgenic Substance , Endocrinology 23:661 ( (Nov.) ) 1938;.
Zuckerman, S.:  Inhibition of Menstruation and Ovulation by Means of Testosterone Propionate , Lancet 2:676 ( (Sept. 18) ) 1937;.
Hartman, C. G.:  Menstruation Inhibiting Action of Testosterone , Proc. Soc. Exper. Biol. & Med. 37:87 ( (Oct.) ) 1937;.
Papanicolaou, G. N., and others:  Inhibitory Effects of Male Sex Hormone on Human Menstruation and Their Evaluation by Vaginal Smears , Proc. Soc. Exper. Biol. & Med. 37:689 ( (Jan.) ) 1938;.
Loeser, A. A.:  Action of Testosterone Propionate on Uterus and Breast , Lancet 1:373 ( (Feb. 12) ) 1938;.
Foss, G. L.:  Action of Testosterone Propionate on Female: Clinical Application and Dosage , Lancet 1:992 ( (April 30) ) 1938;.
Desmarest and Mme. Capitain:  Testosterone Acetate, Therapy of Mastopathies: Seventeen Cases , Presse méd. 45:777 ( (May 26) ) 1937;.
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