While disease of the gallbladder occurs at any age, even in fetuses and newly born infants,1 it is considered primarily a disease of middle age and later life.2 Approximately 16.53 to 214 per cent of patients operated on for symptoms due to disease of the gallbladder are under 30. In an effort to determine the course of the disease before 30 and the end results following cholecystectomy, an analysis was made of sixty-three cases of operation performed during the first three decades of life. These cases represented 21 per cent of 300 consecutive cases in which I had performed the operation.
There were fifty-eight females and five males. The distribution by decades and by sex is shown in table 1.
The ratio of females to males was 12 to 1. This figure is much higher than the ratio for all ages, for which reported values have