We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

ACUTE POLIOMYELITIS:  Relation of Physical Activity at the Time of Onset to the Course of the Disease

JAMA. 1950;142(4):236-241. doi:10.1001/jama.1950.02910220016004.
Text Size: A A A
Published online

It has often been observed by clinicians that certain patients with paralytic poliomyelitis give a history of severe exertion immediately preceding the onset of paralysis. The inference has been that perhaps undue exertion in some way precipitated the paralysis. Trauma preceding onset has also been mentioned as a possible predisposing cause. Recently it has been postulated on both clinical and theoretic grounds that physical activity at a crucial time might be one of the factors which determines the degree of spread of virus in the central nervous system and therefore the severity of the disease.1 Levinson, Milzer and Lewin studied experimentally the effects of fatigue, chilling and mechanical trauma during the incubation period on the resistance of rhesus monkeys to poliomyelitis.2 They found that the incidence and severity of paralysis was greater in monkeys subjected to exhausting exercise or chilling than in control animals; no correlation was demonstrated


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.