This book, as its predecessors, is a verbatim report of a conference of 30 leading investigators in the field of liver disease. As in all Macy Foundation conferences, the discussion is centered around five or six informal papers. In this volume the following subjects are presented: infective hepatitis, George F. Mirick; enzyme activity in human liver, John Waterlow; morphology of the liver, M. M. Hans Elias; the mechanism of biliary excretion in mammals, Elizabeth H. Bagley and Allen L. Grafflin; and hepatic histochemistry, Sten Lagerstedt. Much of the material presented at the conference represents work in progress and is still unpublished. The discussion is informal, extensive, and, because of the character of the participants, highly informative. The volume is well illustrated with tables, graphs, and plates, and reads easily. Pertinent references are included. This is an extremely interesting and stimulating volume, which should be read by all those interested in