Dr.McKeenCattell: Our subject this morning, "The Treatment of Infections of the Genito-Urinary Tract," is one in which there has been a considerable advance in the past few years, an advance which has included the introduction of a number of new drugs. Dr. Modell will open the discussion with a presentation of some of the broader principles of treatment and a consideration of the pharmacology of some of the drugs employed.
Dr.WalterModell: There are four general problems in the treatment of urinary infections: (1) the regulation of urinary volume, (2) the regulation of the urinary pH, (3) the effect of antiseptics on the human host and (4) the effect of the antiseptics on bacteria.
Urinary volume may be shifted in either direction, toward an increase or a decrease. The volume of urine may be increased in an attempt either to flush out the urinary tract or to