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December 17, 1949, Vol 141, No. 16 >

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JAMA. 1949;141(16):1157-1158. doi:10.1001/jama.1949.02910160047013.
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TEMPERATURE OVER 106 F.  DuBois1 cites a survey made by him of 1,761 temperature readings in 357 patients suffering from disease characterized by high temperature. Only 4.3 per cent of the readings were above 106 F. (41.1 C.). None was above 107.8 F. (42 C.); 608 readings came between 104 and 105 F. (40.0 to 40.6 C.). Less than half as many fell between 102 and 103 F. (38.9 to 39.4 C.). It appears from these observations that the "thermostatic level" for the temperature-regulating mechanism was set in the neighborhood of 104 or 105 F. It is a well known fact that human temperature can rise much higher than 106 F. The upper limit, 113 F. (45 C.), has occasionally been recorded. Few persons have survived at this extreme. The safe upper limit of temperature for persons in good condition is closely approached by the fever therapists when they

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