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NEPHRITIS DUE TO SULFONAMIDE DRUGS

Joseph G. Weiner, M.D.
JAMA. 1949;141(14):1010. doi:10.1001/jama.1949.02910140050021.
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ABSTRACT

To the Editor: —  In Current Medical Literature in The Journal, September 17, page 232, Christensen, in his article on "Nephritis Due to Sulfonamide Drugs," is reported to have said "... 2 patients were discharged as subsequently well, but impairment of the renal function still persisting on control after four months shows the grave damage that the kidneys are exposed to in intoxication due to sulfonamide drugs."The reader is left with the impression that the nephritis due to sulfonamide drugs, i. e., lower nephron nephrosis, may progress to a chronic renal disorder. Once the patient has recovered from the acute episode, complete restitution of normal renal function will take place over a period of several months. Irrespective of what the underlying basis may have been for the production of lower nephron nephrosis, whether it be intravascular hemolysis, crush syndrome, thermal burns, uteroplacetal damage or various poisons, the patient either dies

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