L. J. A. Loewenthal, M.D.
JAMA. 1953;152(5):475. doi:10.1001/jama.1953.03690050099028.
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To the Editor:  —Schamberg has recently pictured a lower limb amputation stump showing verrucose changes (J. A. M. A.150:1653 [Dec. 27] 1952). He cited it as an example of confluent, extensive verruca vulgaris but was unable to produce improvement after nine months' vigorous treatment with measures usually employed in the therapy of the common wart. Verrucose changes in the skin accompanying chronic edema have been well recognized for many years (Rojas, H. M.: Sobre la verdadera naturaleza del llamado "pie musgoso," Crón, méd., Lima 40:361, 1923. Pampana, E. J.: Sul "Mossy Foot." Descrizione dei primi casi Colombiani, Arch. ital. di sci. med. colon.10:465, 1929). Though seen in their most florid form in cases of filarial elephantiasis, they are of frequent occurrence in African Negroes suffering from other varieties of chronic edema. I first demonstrated the causative role of chronic lymph stasis in the production of


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