Nicholas J. Galluzzi, M.D.; William Weingarten, M.D.; Frederic D. Regan, M.D.; Alexander A. Doerner, M.D.
JAMA. 1953;152(1):15-16. doi:10.1001/jama.1953.03690010021004.
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The importance of primary hepatic cancer has been stressed in recent reports in the literature. At the United States Public Health Service Hospital, Staten Island, N. Y., we have had the opportunity to study 19 proved cases of primary hepatic carcinoma, with special emphasis on the detailed analysis of hepatic tests as well as the pertinent clinical features. It is well known that primary hepatic cancer is a rare disease in European and North American populations. In Europe, this entity is seen in 0.13% of all autopsies and comprises 1.1% of all carcinomas, and in America, it is seen in 0.25% of all autopsies and comprises 2.1% of all carcinomas, while in the Orient it is seen in 0.85% of all autopsies and comprises 14.1% of all carcinomas. The incidence of hepatic cancer at this institution is unusually high in comparison to that for Europe and North America. This disease


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