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September 24, 1949, Vol 141, No. 4 >
ARTICLE | September 24, 1949

EFFECTS OF SYMPATHETIC NERVOUS SYSTEM

I. M. Hay, M.D.
JAMA. 1949;141(4):280. doi:10.1001/jama.1949.02910040042019.
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ABSTRACT

To the Editor:—  Dr. A. D. Jonas, in his discussion of the article "Some Effects of Myanesin on Psychiatric Patients" (J. A. M. A. 140:1172 [Aug. 6] 1949), remarked: "For the last few years efforts have been made to prevent stimuli originating in the emotional centers of the central nervous system from reaching the effector organs" and, by inference, producing the anxiety state.There are many reasons for believing that such stimuli arise in the sympathetic system itself and produce their effect on the central nervous system by regulating its blood supply. The fact that the sympathetic system is older developmentally is of interest.Also, it is possible that "circulating epinephrine" is the mediator for the heart, sweat glands and the sympathetic nervous system of the brain. Thus the action of the agents would be to inhibit the formation of this mediator. If one further speculates that "circulating epinephrine"

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