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January 14, 1939, Vol 112, No. 2 >
Other Articles | January 14, 1939

THE TREATMENT OF IRON DEFICIENCY ANEMIAS

W. M. FOWLER, M.D.; ADELAIDE P. BARER, Ph.D.
JAMA. 1939;112(2):110-115. doi:10.1001/jama.1939.02800020016004.
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The results obtained by the administration of iron to patients with certain types of secondary anemia are nearly as spectacular in many instances as the effect of liver extract in pernicious anemia. The rapid increase in hemoglobin which follows its use has served to focus attention on iron therapy but has also emphasized the fact that many problems concerning the mechanism of its action are still unsolved. Iron has been raised to the status of a specific remedy, but this has been accomplished more by the better selection of cases for its use than by the introduction of more efficacious preparations. Its routine and somewhat perfunctory use in all cases of secondary anemia has been superseded by the more rational administration of adequate amounts in properly selected cases.

It is well recognized that insufficient iron for hemoglobin formation will lead to anemia of the hypochromic type, characterized by microcytosis and

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