October 29, 1938, Vol 111, No. 18 >

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VITAMIN C IN THE TONSILS AND BLOOD OF CERTAIN CHILDREN

JAMA. 1938;111(18):1660-1661. doi:10.1001/jama.1938.02790440054014.

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The theory that deficiency of vitamin C may be a factor associated with rheumatic fever has been supported by clinical, experimental and epidemiologic data.¹ Studies of 107 children with active rheumatic fever in 1936 indicated a greatly increased metabolic use of vitamin C in those who suffer from the infection which underlies rheumatic fever.² Kaiser and Slavin³ have recently studied the incidence of hemolytic streptococci in the tonsils in relation to the amount of vitamin C in the blood and in the tonsils themselves. One hundred and twenty-three children had been selected by school physicians for tonsillectomy. Five cc. of blood was withdrawn from a vein and a quantitative determination of the content of vitamin C was made the following morning. The tonsils were sent to the laboratory immediately after removal and a quantitative determination of the vitamin C content was made. To determine the presence of

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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VITAMIN C IN THE TONSILS AND BLOOD OF CERTAIN CHILDREN. JAMA. 1938;111(18):1660-1661. doi:10.1001/jama.1938.02790440054014.

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