0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

THROMBOPENIC PURPURA FOLLOWING ALLYLISOPROPYL-ACETYL-CARBAMIDE (SEDORMID)

David B. Hill, M.D.
JAMA. 1938;111(16):1459-1460. doi:10.1001/jama.1938.72790420001010a.
Text Size: A A A
Published online

ABSTRACT

This report is submitted to record the occurrence of the manifestation of purpura in two patients who had been using sedormid (allyl-isopropyl-acetyl-carbamide) as a hypnotic.

Case 1.—  A woman aged 70 complained of the presence of peculiar looking spots in her mouth and on her skin on the morning of Nov. 21, 1936. She presented numerous purplish areas due to extravasation of blood beneath the mucous membrane, inside the lips and cheeks and on the soft palate and edge of the tongue. Several of the lesions were 1 cm. in diameter and some were oozing blood at the edges. Many petechiae were present in the skin of the extremities and body, and ecchymoses at the right elbow and forearm, with smaller areas on the other extremities. The pains experienced in both shoulders during this attack suggested probable extravasation into the joints. Physical examination was otherwise negative. The temperature and pulse

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();