This book represents an analysis of various types of gross prostatic pathologic changes extending over a period of ten years at the Philadelphia General Hospital. Out of a total of 1,215 necropsies, 312 cases, or 25.6 per cent, of gross pathologic changes were found, of which 65 per cent were in white persons and 35 per cent in Negroes. Since numerous investigators have contributed much toward the microscopic side of prostatic pathology, in this treatise the author had only the questionable specimens studied microscopically. Hypertrophy, median bar, carcinoma and abscess were especially studied in regard to their incidence, characteristics, relation to age, clinical conditions, race, and the best type of surgical procedure to be carried out. The book is divided into six chapters. The illustrations show the various characteristic types of prostatic pathologic lesions. Benign prostatic hypertrophy was found to be the most common lesion, with true fibrous median bar