Despite the great interest of the medical profession in inhalation therapy, only a few good monographs on this subject are available. Dautrebande was especially well qualified to write a book on oxygen and carbon dioxide therapy, on the basis of his excellent physiologic background, remarkable knowledge of the literature on the subject, and special interest in the field of group oxygen therapy, to which he was led by his study of war gas poisoning. The first six chapters, presenting the physiology of transport of respiratory gases, the pathophysiologic changes resulting from oxygen want, the effect of carbon dioxide on respiration and circulation, and the physiologic basis for the use of oxygen and carbon dioxide, are excellent. Scant attention, however, is paid to the part played by the breathing mechanism in alveolar ventilation. In the next chapters, VII, VIII, ix and x, a list and a discussion of the clinical conditions