The earlier volumes of this massive work have been reviewed in these pages. Like the others, the present work is a thoroughgoing highly developed analysis of the relationship of certain clinical changes with regard to changes in temperature, polar fronts and other meteorological changes. The book is full of case histories, including reports from the literature; there are a number of graphs in which changes in the weather are correlated with changes in clinical signs; there are several tables, all of which have to do with the thesis which this author has been following for so many pages that weather changes are accompanied by vascular changes which aggravate symptoms and in many cases actually change the course of a disease. The topics covered in this book are infection, inflammation, ulcer of the stomach, Meckel's diverticulum, gallbladder disease, acute pancreatitis, appendicitis, ectopic pregnancy, postoperative complications, vascular accidents, drain abscess, meningitis, orthopedic