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HEALING OF COCCIDIOIDAL GRANULOMA LESION FOLLOWING MEDICINAL THERAPY

Howard A. Ball, M.D.
JAMA. 1932;98(26):2279-2280. doi:10.1001/jama.1932.27320520001007.
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The reports of results of medicinal therapy in cases of coccidioidal granuloma have been disappointing. Because of the effect of iodides in other fungous diseases, probably the method most extensively used in the earlier cases was the internal administration of iodides. The results were not striking. Recently Chipman and Templeton1 reported improvement under oral and intravenous iodide therapy but failed to obtain healing. Their results with antimony and potassium tartrate (tartar emetic) were disappointing, although its use seemed wise following the reports of Guy and Jacob2 and of Tomlinson and Bancroft.3 The latter investivators use local roentgen therapy as well as antimony and potassium tartrate intravenously, so that it is entirely impossible to assign therapeutic values properly, particularly since x-rays have been accorded beneficial effects by earlier workers. Chemotherapy in the form of copper, arsenic or thymol has been disappointing in its results.4 Coccidioidin has not

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