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JAMA. 1938;110(21):1721-1723. doi:10.1001/jama.1938.02790210001001.
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Premenstrual tension is the term applied by Frank1 to a relatively uncommon train of symptoms which occurs cyclically during the premenstruum in certain women of child-bearing age. As current literature is devoid of reports on this subject, its actual incidence cannot be estimated. The fact, however, that my associates and I have encountered the condition in fourteen women during the past three years suggests that it may be more frequent than is now suspected. The opportunity to study and treat ten of the group has led to a plan of management of premenstrual tension which seems to yield excellent therapeutic results and deserves a wider application. In pursuance of the latter thought, this report has been written.

SYMPTOMS  The unpleasant symptoms which 40 per cent of normal women suffer, in varying degrees, before the onset of menstruation are well known. Minor menstrual molimina may be manifest as fatigue, irritability,


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