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ANAEROBIC BETA HEMOLYTIC STREPTOCOCCUS MENINGITIS OF OTITIC ORIGIN TREATED WITH SULFANILAMIDE AND CULMINATING IN COMPLETE RECOVERY

Fred W. Smith, M.D.; Karl F. Mayer; Horst A. Agerty, M.D.; Russell H. Fowler; William C. Layton, M.D.
JAMA. 1938;110(12):887-889. doi:10.1001/jama.1938.62790120001008.
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Although the number of patients who have recovered from meningitis caused by the beta hemolytic streptococcus after treatment with sulfanilamide appears to be growing rapidly, we are able to report for the first time, to our knowledge, a case of meningitis caused by an anaerobic beta hemolytic streptococcus with recovery under sulfanilamide therapy.

REPORT OF CASE  E. B. S., a white girl, aged 21, first seen by one of us July 29, 1937, complained of sore throat and backache. The past personal and family histories were noncontributory. The temperature was 103.4 F. and the throat was acutely inflamed and covered with numerous white patches. A culture was taken and the following day was reported as showing a few pneumococci, Streptococcus viridans and Micrococcus catarrhalis. In the meantime she had been given 10 grains (0.65 Gm.) of sulfanilamide three times a day. This was discontinued the following day after we received

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