This was written primarily for students in veterinary medicine, but little of the original material is derived from veterinary sources. The references accompanying each section duplicate closely those found in textbooks of advanced physiology for medical students. Furthermore, the comparative physiology of domestic animals has scarcely received the attention that might be expected from the veterinary group. Examination of the text shows a surprising dearth of discussion from a comparative point of view. Only occasionally are there references to differences in physiologic behavior in different species, the most complete presentation being in the sections on nutrition and metabolism and on reproduction. The textual material is conventionally sound, clearly presented and well arranged and is sufficiently advanced to be useful to medical students as a reference work.