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Ward J. MacNeal, M.D.; Michael E. Cavallo, M.D.
JAMA. 1937;109(26):2139-2141. doi:10.1001/jama.1937.92780520001008.
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In recent medical literature there have been increasingly frequent reports of the successful care of patients afflicted with infections formerly regarded as almost certainly fatal. So far as we are aware, however, recovery of a patient with bacteremia accompanied by evidence of obstruction in the cavernous sinuses still remains a medical rarity. Cavenagh1 was able to find only seven reported recoveries from acute thrombosis of the cavernous sinus. Three patients recovered after surgical drainage of the sinus and of these only one had a positive blood culture (Staphylococcus aureus). Four patients recovered after anti-infective therapy. Three of these cases were due to Staphylococcus aureus, and this organism was recovered from the blood stream in two of the patients. One of these patients with bacteremia received only transfusions. The other two patients were treated with bacteriophage. The fourth patient in this group given anti-infective therapy appears not to have


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