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JAMA. 1937;109(25):2072-2073. doi:10.1001/jama.1937.02780510046015.
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CANADIAN EXPERIENCE WITH ZINC SULFATE SPRAYS FOR PREVENTION OF POLIOMYELITIS  The serious outbreak of poliomyelitis in and around Toronto this year afforded an exceptional opportunity for the study of the prophylactic value of zinc sulfate sprays. The report by Tisdall and his co-workers 1 on this subject deserves careful study. A trial of nasal spraying was approved by the Department of Health of Ontario on August 29. It was agreed that each child should be sprayed on two occasions, ten or twelve days apart, and that from 0.5 to 1 cc. of the solution should be placed in each naris in each spraying. The solution contained 1 per cent zinc sulfate, 1 per cent pontocaine and 0.5 per cent sodium chloride. The spraying was done according to the technic of Peet, Echols and Richter but differed from their recommended procedure in that it was not administered on three successive days,


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