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FURTHER STUDIES WITH THE TUBERCULIN OINTMENT PATCH TEST

ERNST WOLFF, M.D.; SAMUEL HURWITZ, M.D.
JAMA. 1937;109(25):2042-2044. doi:10.1001/jama.1937.02780510016005.
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In previous communications1 reference was made to the value of the ointment patch test in the diagnosis of tuberculosis. It was shown that the ease of application, the stability of the preparation and the high percentage of agreement with the Mantoux test (0.1 mg. of old tuberculin) made this method a most desirable one for general practice. These previous reports deal with a total of some 800 observations. In the present paper we enlarge on our previous results and report our experience with approximately 1,000 new patients.

HISTORICAL REVIEW  In 1907 Moro2 first described an inunction method for the diagnosis of tuberculosis. This ointment consisted of 50 per cent old tuberculin in a base of hydrous wool fat. This, however, proved too insensitive for general use. Nevertheless it stimulated many attempts to improve on the percutaneous method. Hamburger3 introduced the so-called perkutan ointment, which consisted of old

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