This volume is based on a course of twenty lectures delivered at the College of France. The author discusses the nature of pain and its physiology. The general plan of surgery for the relief of pain is described. Leriche's aim is to clarify several aspects of the problem of pain in which, for the past several years, surgery has given us an entirely new conception. The painful conditions the surgical therapy of which is discussed include trigeminal neuralgia, painful neuromas, causalgia, painful amputation stumps, painful vasoconstrictions and Raynaud's disease, arteritis, angina pectoris, painful scars and inoperable cancers. The book is well indexed and printed. Leriche is an earnest student and experienced teacher of this subject and his voice is that of authority. The book is of value to all interested in this subject.