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JAMA. 1937;109(18):1456-1457. doi:10.1001/jama.1937.02780440046017.
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The recent wave of enthusiasm over the injection method of hernia had its impetus in the successes of.sclerotherapy in varicose veins and hemorrhoids. Some disappointment with the results of surgical procedures, particularly in cases of direct inguinal hernia, was an additional reason for the revival of a method long relinquished and tainted by quackery.

According to recent reports by Bratrud, Rice, Harris and White, and Fowler the rationale of the treatment depends on the property of mildly irritant solutions to produce a fibrosis when injected into normal tissues, and on the ability of the fibrosis thus produced to obliterate the inguinal canal by causing an intimate adherence of the muscular layers in this region by much the same mechanism as that obtained by suturing. Harris and White1 injected such irritants into the muscles of the thigh in a group of normal guinea-pigs. They found that these solutions provoked a


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