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W. D. Ludlum, M.D.
JAMA. 1937;109(14):1142-1143. doi:10.1001/jama.1937.02780400058021.
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To the Editor:—  The excuse for this letter is the difficulty which the deleterious effects of an exploited remedy have in catching up with its recorded virtues.My first opportunity to employ zinc sulfate for the prevention of poliomyelitis was for the protection of the mother of a little patient. The instructions with regard to material, instruments and technic, as recommended in the Peet article, were carefully carried out. The mucosa was shrunken with epinephrine and the zinc sulfate 1 per cent, sodium chloride 0.5 per cent, pontocaine hydrochloride 1 per cent solution was applied under visual control to the olfactory area. The young woman commented that she felt as if she were going to have her tonsils out again, but only after leaving did she begin to be distressed. She complained that the sensation in her nose was like red hot irons. It lasted through the night, the application


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