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ACTIVE IMMUNIZATION OF TUBERCULOUS CHILDREN AGAINST WHOOPING COUGH WITH SAUER'S VACCINE

MORRIS SIEGEL, M.D.; ESTHER W. GOLDBERGER, M.D.
JAMA. 1937;109(14):1088-1092. doi:10.1001/jama.1937.02780400004002.
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Shortly after Sauer's early reports of his success in the prevention of whooping cough with doses of 80 billion bacilli of an unwashed vaccine prepared from freshly isolated strains of Haemophilus pertussis, it was decided to test the effectiveness of the vaccine at Sea View Hospital under adequate control conditions.

At Sea View Hospital tuberculous persons of all ages are admitted from hospitals and homes of New York City and hospitalized for the duration of their illness. In the pediatrics service there are almost 200 patients under 16 years of age with tuberculosis or suspected of having tuberculosis. The average duration of hospitalization for the tuberculous children is about two years. Newly admitted children are kept in the pediatrics admitting ward for several weeks and are then transferred to one of the other wards. For those over 6 years of age there is a separate ward for boys and girls.

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