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THE TOXICOLOGY OF NEW INDUS TRIAL COMPOUNDS

JAMA. 1937;109(12):956. doi:10.1001/jama.1937.02780380040011.
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The introduction into industry of many new synthetic chemical compounds has created innumerable diagnostic and other clinical problems for the medical profession. McConnell1 has indicated the nature of this development. The House of Delegates at the Atlantic City session, this year, authorized the establishment of a Council on Industrial Hygiene. Laboratories for the investigation of the toxicologic and pharmacologic properties of such compounds are now being developed in many industries.

In spite of this increasing recognition, medicine is frequently put in the position of attempting to lock the door after the horse has been stolen. Many industrial compounds have received wide use and caused considerable damage before their destructive properties have received sufficient investigation. An example is manifest from the study made by Lehman and Newman 2 of the Stanford University School of Medicine on propylene glycol, which has had wide use as a solvent for technical purposes. They

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