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JAMA. 1937;109(5):367. doi:10.1001/jama.1937.02780310045017.
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ABSTRACT

Dr. Francis Ill with Relapsing Fever  Dr. Edward Francis, U. S. Public Health Service, is at the Marine Hospital, Baltimore, slowly recovering from relapsing fever, according to the New York Times. It was stated that Dr. Francis allowed himself to be bitten by a tick in a laboratory experiment. For five years he kept thirty ticks, infected with relapsing fever, in a pill box without food or water, according to the newspaper report. Then a monkey bitten by one of these in an experiment developed the disease, proving that five years' starvation not only did not kill the ticks but did not kill the organisms they harbored. To determine whether the organism is transmitted to later generations of ticks and whether it was still capable of causing the disease, Dr. Francis allowed a second generation tick to bite him and as a result he developed the fever. Dr. Francis graduated

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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