0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

CHOLESTEROSIS OF THE GALLBLADDER

JAMA. 1937;108(24):2042-2043. doi:10.1001/jama.1937.02780240034012.
Text Size: A A A
Published online

Virchow in 1857 described a peculiar stippled appearance of the mucosa of some gallbladders removed during necropsies. He regarded the yellow flecks and strands as fatty infiltration and suggested that the material is a neutral fat excreted by the liver and reabsorbed from the bile by the epithelial cells of the gallbladder mucosa. The condition received scanty attention from surgeons and pathologists, despite its not infrequent occurrence and a striking gross appearance.

Aschoff1 demonstrated in 1906 the occurrence of cholesterol in the epithelial cells of the mucous membrane of the gallbladder. Moynihan2 in 1909 presented an excellent description of the naked eye appearance of cholesterosis, calling attention to the yellow stippling of the mucosa. He regarded the discoloration as the result of an inflammatory process in which the epithelium was desquamated and the underlying tissue became bile stained. In six of his cases of this type, relief from

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();