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VINCENT'S STOMATITIS AND GRANULOCYTOPENIA

David Christie, M.D.
JAMA. 1937;108(19):1668. doi:10.1001/jama.1937.02780190084022.
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ABSTRACT

To the Editor:—  That no mention of agranulocytic angina or granulocytopenia was made by Farrell and McNichols in their article on the efficacy of various medicaments in the treatment of Vincent's stomatitis (The Journal, February 20) is a surprising omission. Attention should be called to the necessity for a leukocyte and a differential count in any case of severe stomatitis, no matter what organisms are found in the mouth. Certainly the blood smear should be examined before using neoarsphenamine or strong local applications advised elsewhere. In the article referred to, three cases of noma are reported without mention of the leukocyte count, although a benzene nucleus was given therapeutically in cases 1 and 2. A patient with Vincent's stomatitis with granulocytopenia under my care received poor treatment and I feel that this point should be drawn to the attention of your readers to save others from similar error. No practitioner

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