To write a concise and comprehensive textbook on the fundamentals of pharmacology which will meet the needs of both students and practitioners and at the same time stimulate the interest of investigators is not an easy task. Dr. Thienes has written a book to meet these requirements. The book is divided into twelve sections, beginning with the systematically acting drugs the effects of which are better understood. Central nervous stimulants and depressants, drugs acting on the peripheral nervous system, drugs acting on the muscles and diuretics occupy the first half of the book. This is followed by antiparasitic drugs, hormones, minerals, tissue extracts and vitamins. Expectorants, emetics and cathartics are included in the section on drugs used because of local action on body surfaces. Chemical diagnostic agents and actions of drugs on cells are treated in two separate sections. Pharmacy and prescription writing form the last section of the book.