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Council on Pharmacy and Chemistry

JAMA. 1937;108(9):722-727. doi:10.1001/jama.1937.02780090034012.
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The following information regarding the firms mentioned in the report is noted: Firm 2 is no longer in existence. The Council has received information that no sutures have been manufactured by this firm since 1920, when it was taken over by another firm, and that the latter firm discontinued the preparation of tubed catgut in 1925, though through an oversight it was still advertising ligatures in 1936 in a medical journal. The sutures marketed by firm 8 were actually manufactured for it by another firm and were not being sold by it at the time of this report. The firm merely sent the sutures for academic interest. Therefore, no direct responsibility is attached to firm 8 in this instance. On October 30 firm 9 wrote that the old ligature material to which this investigation refers has been withdrawn from the market and that its ligatures and sutures are now being manufactured by the Heat Sterilization Method approved by the British Ministry of Health. The firm states that every batch of ligatures prepared is now tested bacteriologically by an outside bacteriologist. The Council commends the firm for its prompt action taken at the difficult period of reorganizing its pharmaceutical department. On November 17, 1936, firm 9 reported as follows: "We attach herewith the original certificates of tests on all Surgical Ligatures manufactured under our new process. All batches have proved Sterile when tested according to the Meleney-Chatfield technique by the independent Bacteriologist who tests all our material."
Bulloch, W.; Lampitt, L. H., and Bushill, J. H.: The Preparation of Catgut for Surgical Use, British Medical Research Council Special Report Series, 138, 1929.
Meleney, F. L., and Chatfield, Mabel:  The Sterility of Catgut in Relation to Hospital Infections, with an Effective Test for the Sterility of Catgut , Surg., Gynec. & Obst. 52:430 (Feb., No. (2 A) ) 1931.
Clock, R. O.:  The Fallacy of Chemical Sterilization of Surgical Catgut Sutures , Surg., Gynec. & Obst. 56:149, ( (Feb.) ) 1933.
Information obtained from manufacturers of sutures is given in table 1.
Brown, J. H.:  An Improved Anaerobe Jar , J. Exper. Med. 33: 677 ( (June) ) 1921;
35:467 (April) 1922.
Soule, Malcolm: Personal communication to the author from Hygienic Laboratory, University of Michigan.
Clock, R. O.:  A Reliable Method for Testing the Sterility of Surgical Catgut Sutures , Surg., Gynec. & Obst. 61:789 ( (Dec.) ) 1935.
Hill, H. B.: J. Applied Microscopy 3, No. (8) .
Sanderson, E. S.:  A Note on the Sterilization of Surgical Instruments , J. Lab. & Clin. Med. 7: 360 ( (March) ) 1922.


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