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THROMBO-ANGIITIS OBLITERANS AND ADDISON'S DISEASE IN THE SAME PATIENT

Samuel Silbert, M.D.
JAMA. 1937;108(7):551-552. doi:10.1001/jama.1937.92780070004010c.
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Since there is no record in medical literature of the occurrence of thrombo-angiitis obliterans and Addison's disease in the same patient, the following case is of unique interest :

H. G., a white youth, aged 20 years, seen in April 1935, stated that he was in excellent health until the summer of 1934, when he began to complain of pain in the toes of the left foot. This was thought to be due to a weak metatarsal arch. About two months later he first noticed pain in the left calf on walking and then found that he could not walk more than three blocks without stopping to rest. In December 1934 he observed that the left great toe became blue whenever it was put in warm water. In January 1935 ulceration developed in this toe and his physician applied a tannic acid dressing, following which gangrene of

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