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THE RELATIVE IN VITRO ACTIVITY OF CERTAIN ANTISEPTICS IN AQUEOUS SOLUTION

ROBERT N. NYE, M.D.
JAMA. 1937;108(4):280-287. doi:10.1001/jama.1937.02780040030007.
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In the past ten years, innumerable articles concerning antiseptics have been published. Hardly a year passes without the appearance of a new proprietary bactericide. In advertisements in medical journals, magazines and newspapers and even in programs over the air the marvelous germ-killing properties of this or that antiseptic are brought to one's attention. Less credulous physicians are puzzled as to the solution of choice, whereas the more credulous are easily influenced by the astonishing claims of the manufacturers of certain solutions. One only needs consult the pharmacist of a large general hospital to learn of the many kinds of antiseptic solutions that are demanded by different staff physicians.

The experiments subsequently described were undertaken in an effort to determine the relative in vitro activity of certain proprietary and nonproprietary solutions which are ordinarily used as antiseptics for minor wounds and for irrigations. It is hoped that the accumulated data will

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