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David Hoehn, M.D.
JAMA. 1945;128(7):513. doi:10.1001/jama.1945.92860240002010a.
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A white boy aged 3 years was admitted to the hospital on Aug. 4, 1944, acutely ill with generalized edema. The swelling was most noticeable in the lower extremities, and the scrotum was about the size of a large grapefruit.

Urinalysis showed pus, albumin and no casts. A diagnosis of pyelonephritis or nephrosis was made on admission.

During the next few days the swelling decreased and the boy's general condition improved. However, a week later he had more edema, and three weeks after admission the edema became very pronounced again. At that time he was seen in consultation by Capt. H. A. Zimmerman, M. C., whose diagnosis was that of nephrosis.

I tried to elicit some information that might give a clue as to the source of the kidney damage. The child had always been well, and the fact that he was taken seriously ill so suddenly made me


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