The disease entities discussed are described by their common designations Hodgkin's disease, chronic lymphatic leukemia and chronic myelogenous leukemia. Various attempts to classify them on the basis of stem cell or morphologic grounds and the merits of the controversy as to whether one or the other is an infectious process need not detain one. For all essential purposes they involve radiosensitive tissues and behave like neoplastic processes, terminating almost invariably in death.
This report covers a ten year period (1925-1935) and includes only cases that have been checked by biopsy, adequate blood studies and postmortem examination. All sections have been reviewed recently and confirmed by Dr. Frederic Parker, pathologist, and Dr. Henry Jackson of the Lymphoma Clinic of the Boston City Hospital. Any doubtful case has been discarded. Any patient who has been lost to follow up has been considered dead. Any leukemia of less than three months' duration has