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JAMA. 1945;128(1):1-6. doi:10.1001/jama.1945.02860180003001.
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When I was a young physician Dr. Frank Billings was one of the most distinguished figures in American medicine. I looked on him with admiration and awe. Therefore, to be asked to give this lecture, founded to perpetuate his memory, is not only an honor but also a source of great pleasure. My only regret is that I have not a more worthy tribute for the occasion.

The subject of mediastinal emphysema is not a new one. Occasional cases with dramatic symptoms were reported a century or longer ago. However, during the past twenty years, especially during the past decade, experimental investigation and clinical observation have' extended our knowledge and put it on a firm base. The conditions causing mediastinal emphysema are now well known; the mechanism of its production and its relation to associated manifestations, chiefly interstitial emphysema of the lungs and pneumothorax, have been clearly exposed; the symptoms


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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