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JAMA. 1936;107(19):1562. doi:10.1001/jama.1936.02770450046014.
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The idea that fats retard digestion is an ancient one. Aristotle had evidently observed evidence for this before he expressed the opinion "Now the best digestion is in the bottom of the stomach, because the fat descends not there; such as eat fat meat are verysleepy, by reason that digestion is hindered." This observation has been repeatedly confirmed in more modern studies of gastro-intestinal function. The researches of Cannon1 are particularly clear in demonstrating the delay in emptying time of the stomach following a fat meal, as compared to the rate of passage of food from the stomach after protein or carbohydrate ingestion. The introduction of x-ray technic made it possible to observe, under normal conditions, both gastric peristalsis and the exit of food through the pylorus. Although the earlier studies emphasized the effect of fat on motility of the stomach and on the control of the pylorus, it


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